Downloads: 21
Mr. Shashi Bhushan & Prof. Amaresh kumar
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11606 - 11611
Downloads: 188
Prof. B. J. Mundhe
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11621 - 11622
Downloads: 19
Mitra Mondal
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11623 - 11625
Downloads: 175
Shri. Nanasaheb Walmik Kurhade
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11626 - 11631
Downloads: 204
Prof. Priya Bhushan Kapadne
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11632 - 11640
Downloads: 173
Vidya N. Jadhav & Sujata P. Pawar
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11641 - 11644
Downloads: 239
Shalaka Wikhe, Prof Nutan Deshmukh & Kuldeep Deshpande
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11645 - 11648
Downloads: 204
Manju Maria Solomon
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11654 - 11649
Downloads: 171
Priyadarshani B. More
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11655 - 11660
Downloads: 224
Priyadarshani B. More
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11661 - 11665
Downloads: 220
V. S. Sumi
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11666 - 11671
Downloads: 165
Tina Roy & Karuna Gupta
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11673 - 11679
Downloads: 177
K. Sheeba
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11680 - 11689
Downloads: 201
Anand B. Dadas
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11690 - 11701
Downloads: 143
Jaskaran Kaur
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11703 - 11708
Downloads: 288
Jayeeta Bagchi
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11709 - 11717
Downloads: 157
Anadi Kumar Mishra & Vinod Kumar Mishra
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11718 - 11722
Downloads: 148
Subhash Singh
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11723 - 11730
Downloads: 147
Gulshan Yadav & Shipra Singh
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11732 - 11737
Downloads: 135
Jyoti Singh
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11738 - 11741
Downloads: 137
M. P. Tripathi
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11742 - 11748
Downloads: 152
Santosh Kumar Singh & Nidhi Singh
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11749 - 11752
Downloads: 183
Nitin Singh
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11753 - 11766
Downloads: 203
Pradeep Kumar & Prof. S.K. Verma
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11767 - 11776
Downloads: 142
Rachana Srivastava & Manisha Kindo
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11777 - 11786
Downloads: 139
Reena Trivedi
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11787 - 11792
Downloads: 146
Sandeep Tiwari
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11793 - 11800
Downloads: 191
Bhagwati Thite
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11801 - 11814
Downloads: 149
Alice Nessy. K
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11815 - 11819
Downloads: 144
Shaheen Parveen & Seema Dhawan
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11820 - 11825
Downloads: 130
Ramendra Kumar Gupta
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11826 - 11832
Downloads: 164
Ajay Kumar Singh
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11726 - 11728
Downloads: 710
Dharmendra Kumar Vaishya
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11729 - 11734
Downloads: 169
Dinesh Bahadur Singh
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11735 - 11738
Downloads: 126
Faisal Isa & Vidhu Shekhar Pandye
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11739 - 11742
Downloads: 318
Lajo Pandye
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11743 - 11747
Downloads: 509
Santosh Kumar Singh
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11748 - 11751
Downloads: 337
Vinod Kumar
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11752 - 11754
Downloads: 142
Prof. S. D. Sharma & Ms Pooja Shahi
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11755 - 11760
Downloads: 132
Prof. S. D. Sharma & Ms Pooja Shahi
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11761 - 11770
Downloads: 131
Prof. S. D. Sharma & Mr. Mohd. Ijlal Anjum
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11771 - 11777
Downloads: 151
Subhash Singh
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11778 - 11789
Downloads: 180
Triveni Singh
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11790 - 11795
Downloads: 181
Sipra Ray
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11796 - 11802
Downloads: 23
Seema Sidana & Onkar Nath Mishra
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11803 - 11805
Downloads: 135
Mahavir Singh Chhonkar
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11806 - 11809
Downloads: 169
Mohinder Kumar Slariya
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11810 - 11822
Downloads: 145
Shubhangi S. Kurhade
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11810 - 11822
Downloads: 160
Mr. Krushnavadan R. Parmar
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11823 - 11829
Downloads: 150
Minakshi
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11830 - 11835
Downloads: 138
Dharvesh Katheriya, Bharat Panda, Avinash Tripathi, Padma Verma, Neeraj Kumar Singh & Anuradha
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11836 - 11844
Downloads: 156
R. J. Patil & K. S. Charak
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11845 - 11855
Downloads: 143
Vijayalaxmi Rajiv Shinde
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11856 - 11870
Downloads: 166
Dharvesh Katheriya, Bharat Panda, Avinash Tripathi, Padama Vaerma, Neeraj Kumar Sinh, & Anuradha
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11871 - 11884
Downloads: 178
Dhananjay Baburao Lokhande
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11871 - 11878
Downloads: 152
Suresh G. Isave
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11879 - 11882
Downloads: 191
Rekha Rani
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11883 - 11887
Downloads: 284
Prof. Kirankumar Kavathekar
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11883 - 11887
Downloads: 138
Dharambeer Singh
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11888 - 11891
Downloads: 151
Rajesh Kishor Tripathi
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11892 - 11896
Downloads: 147
Padama Tripathi
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11897 - 11901
Downloads: 169
Shivraj Singh Yadav
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11902 - 11910
Downloads: 138
Vasiraju Rajyalakshmi
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11911 - 11926
Downloads: 145
Nitin Mohod & Mohan S. Kashikar
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11927 - 11933
Downloads: 167
Neeru Vasishth & V. Rajyalakshmi
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11934 - 11944
Downloads: 127
Sameer Arun Butala
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11945 - 11948
Downloads: 137
Ramesh Bhavisetti
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11949 - 11956
Kaushal Kishor Singh & Yogendra Kumar Saraswat
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11957 - 11965
Downloads: 176
Davender Singh Yadav & Satnam Singh
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11966 - 11970
Downloads: 172
Yatharth N. Vaidya
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11966 - 11970
Downloads: 237
Dr. Mukesh Kumar
Received Date: 25/02/2019 | Accepted Date: 28/02/2019 | Published Date: 04/03/2019
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11981 - 11990
Downloads: 104
Dr. Akhilesh Kumar Singh
Received Date: 25/02/2019 | Accepted Date: 28/02/2019 | Published Date: 04/03/2019
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11991 - 11996
Downloads: 92
Dr. Manjeet Singh Bhandari
Received Date: 25/02/2019 | Accepted Date: 28/02/2019 | Published Date: 01/03/2019
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 11997 - 11999
Downloads: 65
Dr. Mritunjay Kumar
Received Date: 25/02/2019 | Accepted Date: 28/02/2019 | Published Date: 01/03/2019
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 12000 - 12005
Downloads: 11
Dr. Anjana Jadon
Received Date: 25/02/2019 | Accepted Date: 28/02/2019 | Published Date: 01/03/2019
Issue: Jan-Feb, 2019 | Volume/Issue:6/49 | Page No.: 12006 - 12018
Present investigation was aimed to evaluate the hepatoprotective effect of Terminalia belerica fruit extract at four different doses (100, 200, 400 and 800 mg/kg, p.o.) against acetaminophen (APAP, 2.0 g/kg, p.o. once only) induced liver injury in female albino rats. APAP administration caused significant increase in the activities of serum transaminases, alkaline phosphatase and lactate dehydrogenase (P < 0.05). Toxicant caused injury in the parenchymal cells thereby affecting triglycerides, cholesterol, total and direct bilirubin level. A significant decline was observed in total protein content, blood sugar level and glycogen content whereas level of albumin increased during toxicity. Hepatic lipid peroxidation increased significantly on the contrary significant depletion was observed in reduced glutathione level after acetaminophen administration (P < 0.05). Activities of hepatic microsomal drug metabolizing enzymes i.e. aniline hydroxylase and amidopyrine-N-demethylase were inhibited significantly after APAP intoxication. Single administration of extract after toxicant administration significantly reversed the APAP induced alterations in the liver function tests and drug metabolizing enzymes. All biochemical results indicated that 400 and 800 mg/kg dose of extract were equally effective when analyzed statistically. It was observed that acetaminophen caused significant histopathological damage (inflammation, necrosis and vacuolation) in hepatocytes. These changes were recouped with therapy of extract (400 mg/kg). Thus it may be concluded that Terminalia belerica extract possessed considerable hepatoprotective potential.